RNA-seq of cells with centrosome amplification

NIAID Data Ecosystem2026-05-01 收录

中心体扩增

细胞侵袭与增殖调控

数据链接：

https://www.ncbi.nlm.nih.gov/sra/ERP132994 数据链接链接失效反馈

官方服务：

资源简介：

Centrosome amplification induces proliferation arrest and cell invasion. The fate of centrosome amplification cells are studied here.

创建时间：

2023-10-13

Amplified centrosomes may underlie aggressive disease course in pancreatic ductal adenocarcinoma

胰腺癌

中心体扩增

Centrosome amplification (CA), the presence of centrosomes that are abnormally numerous or enlarged, is a well-established driver of tumor initiation and progression associated with poor prognosis acr

DataCite Commons2020-08-25 更新50

Supplementary Table from Proteomic Mapping and Targeting of Mitotic Pericentriolar Material in Tumors Bearing Centrosome Amplification

肿瘤蛋白质组学

中心体扩增

Supplementary Table from Proteomic Mapping and Targeting of Mitotic Pericentriolar Material in Tumors Bearing Centrosome Amplification

NIAID Data Ecosystem20

Oncogene-like induction of cellular invasion from centrosome amplification

癌细胞侵袭

中心体扩增

Centrosome amplification has long been recognized as a feature of human tumors, however its role in tumorigenesis remains unclear. Centrosome amplification is poorly tolerated by non-transformed cells

NIAID Data Ecosystem20

PPARγ promotes diabetes-associated centrosome amplification via increasing the expression of SKA1 directly at the transcriptional level

糖尿病分子机制

中心体扩增

We have published recently that type 2 diabetes can induce cell centrosome amplification, due to the action of high glucose, palmitic acid and insulin, and ROCK1 and 14-3-3σ are signal mediators. In t

NIAID Data Ecosystem40

Oncogene-like induction of cellular invasion from centrosome amplification. Homo sapiens

中心体扩增

癌细胞侵袭

NIAID Data Ecosystem20