Genome sizes and mutation rates of pol2-4 msh6Δ sequenced lineages.

aLineages C, F, G1, G2, and H were grown on synthetic complete (SC) media. Lineages B, D, and E were grown on synthetic complete media without uracil and leucine (SC-Ura-Leu) to select for double mutant spores containing the URA3 and LEU2 transgenes linked to the mutator alleles.bThe sequenced genome size equals the number of base-pairs of the genome confidently scored in all members of a lineage.cValues below this heading should be multiplied by 10-7 mutations/base-pair/cell division.dObtained by multiplying the sequenced genome size by the number of cell divisions scored.eThe value below this heading was determined by dividing the total number of mutations by the number of cell divisions and the total base-pairs confidently scored. It should be multiplied by 10-7 mutations/base-pair/cell division.Genome sizes and mutation rates of pol2-4 msh6Δ sequenced lineages.