ChIP-seq analysis of RNA polymerase I inhibitor effect on Pol I and Pol II binding
收藏NIAID Data Ecosystem2026-05-02 收录
下载链接：
https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE267504
下载链接
链接失效反馈官方服务：
资源简介：
Ribosome biosynthesis is essential for cancer growth and proliferation. This dependency is therapeutically exploitable by blocking the rate-limiting step, RNA polymerase I (Pol I) transcription. Here we investigated the effects of RNA Pol I inhibitor on binding of Pol I RPA1 and Pol II Rpb1 on genomic DNA. We treated LNCaP prostate cancer cells with either DMSO vehicle or 1 microM BMH-21 for 6 hrs.
创建时间：
2025-08-12
