Malaria vaccine: immunization of mice with a synthetic T cell helper epitope alone leads to protective immunity.
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The circumsporozoite protein contains multiple tandem copies of the sequence DPPPPNPN. High titer antibodies to the epitope were detected in sera from mice immunized with a MAP construct containing a linear peptide of the epitope C-terminal to a T cell epitope, derived from residues 20-39 of the P. berghei CS protein.
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IEDB创建时间：
1993-01-01
