Development and validation of a postoperative delirium prediction model for patients admitted to an intensive care unit in China: a prospective study

Objectives We aimed to develop and validate a postoperative delirium (POD) prediction model for patients admitted to the intensive care unit (ICU). Design A prospective study was conducted. Setting The study was conducted in the surgical, cardiovascular surgical, and trauma surgical ICUs of an affiliated hospital of a medical university in Heilongjiang Province, China. Participants This study included 400 patients (≥18 years old) admitted to the ICU after surgery. Primary and secondary outcome measures The primary outcome measure was postoperative delirium assessment during ICU stay. Results The model was developed using 300 consecutive ICU patients and was validated using 100 patients from the same ICUs. The model was based on five risk factors: Physiological and Operative Severity Score for the Enumeration of Mortality and Morbidity; acid-base disturbance; and history of coma, diabetes, or hypertension. The model had an area under the receiver operating characteristics curve of 0...