Crystal structure of SADS-CoV main protease (Lys35Val/Cys224Ser) in complex with SY110
收藏Protein Data Bank Japan2026-03-18 更新2026-04-19 收录
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Crystal structure of SADS-CoV main protease (Lys35Val/Cys224Ser) in complex with SY110 Descriptor: (1~{R})-3,3-bis(fluoranyl)-~{N}-[(2~{R})-3-methoxy-1-oxidanylidene-1-[[(2~{R},3~{S})-3-oxidanyl-4-oxidanylidene-1-phenyl-4-(1,3-thiazol-2-ylmethylamino)butan-2-yl]amino]propan-2-yl]cyclohexane-1-carboxamide, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, ORF1ab polyprotein, ... Authors: Zeng, R, Lei, J. Deposit date: 2025-07-14 Release date: 2026-02-18 Last modified: 2026-03-18 Method: X-RAY DIFFRACTION (2 Å) Cite: An intrinsic loop-mediated structural stability modulating inhibitor potency in the SADS-CoV and SARS-CoV-2 main proteases. Plos Pathog., 22, 2026
创建时间：
2025-07-14
