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Loss of p21 expression enhances DNA damage, cholestasis and hepatocarcinogenesis in the liver. Mus musculus

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NIAID Data Ecosystem2026-03-08 收录
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Overexpression of p21 in NEMOΔhepa animals protects against DNA damage, acceleration of hepatocarcinogenesis and cholestasis. As strengthened by our LPS stimulation experiments, we identified a novel protective role of p21 against DNA damage. Overall design: Expression profiling of livers from wild type, NEMO, and NEMO-P21 null mice.

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2014-09-03
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