five

A comparative analysis of microglial inducible Cre lines

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https://www.ncbi.nlm.nih.gov/sra/SRP405742
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资源简介:
We investigated the effects of tamoxifen, CreER recombination, and genetic manipulations to genes whose promoters are used to driving CreER expression on microglial gene expression across 4 different microglial inducible Cre lines. Overall design: CreER-expressing mice were injected with tamoxifen (100 mg/kg) or oil i.p. once daily from P28 to P31. 4 weeks later, at P56, microglia were isolated by FACS from the brains of the mice. RNA was isolated from the collected microglia used for RNA sequencing.
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2024-06-07
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