Benchmarks of the 2-step pipeline on NA12878 exome (Basic protocol 1).

In elPrep, the combined execution of both preparation steps is faster than running the steps one after the other. When elPrep gets to use a similar amount of RAM as Picard uses, it executes the pipeline three times faster than Picard (third column). When elPrep is given access to all available RAM, it executes the pipeline five times faster than Picard (fourth column). Benchmarks of the 2-step pipeline on NA12878 exome (Basic protocol 1).