Gene expression profiles in GSK-3beta Ser9Ala knock-in mouse heart
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资源简介：
GSK-3 is a serine-threonine protein kinase and consists of two isoforms, GSK-3alpha and GSK-3beta. GSK-3alpha and GSK-3beta are inactivated by phosphorylation at Ser21 and Ser9, respectively. GSK-3alpha Ser21Ala and GSK-3beta Ser9Ala phosphorylation-resistant knock-in mice have constitutively active form of GSK-3. Gene expression in GSK-3alpha Ser21Ala knock-in, GSK-3beta Ser9Ala knock-in, or wild-type mouse hearts were analyzed at baseline. Please note that the wildtype samples were normalized twice for a separate analysis of GSK-3alpha vs wildtype and GSK-3beta vs wildtype. The wildtype samples are included on both series but are the same samples with identical CEL files.
创建时间：
2019-06-17
