Crystal structure of the ScFv-5E5 in complex with a Tn glycopeptide

Crystal structure of the ScFv-5E5 in complex with a Tn glycopeptide Descriptor: (2~{S})-~{N}-[2-[[(2~{S})-1-[[(2~{S},3~{R})-3-[(2~{S},3~{R},4~{R},5~{R},6~{R})-3-acetamido-6-(hydroxymethyl)-4,5-bis(oxidanyl)oxan-2-yl]oxy-1-[[(2~{S})-1-[(2~{S})-2-aminocarbonylpyrrolidin-1-yl]-1-oxidanylidene-propan-2-yl]amino]-1-oxidanylidene-butan-2-yl]amino]-3-oxidanyl-1-oxidanylidene-propan-2-yl]amino]-2-oxidanylidene-ethyl]-1-[(2~{S})-2-azanylpropanoyl]pyrrolidine-2-carboxamide, Heavy chain of our ScFv-5E5, Light chain of our ScFv-5E5 Authors: Macias-Leon, J, Corzana, F, Hurtado-Guerrero, R. Deposit date: 2019-12-09 Release date: 2020-11-18 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody. Chem.Commun.(Camb.), 56, 2020