Single-cell RNA-seq and single-cell ATAC-seq of in vitro polarized mouse Th17 and Th1 cells

We generated droplet-based single-cell RNA-seq profiles of non-pathogenic Th17, pathogenic Th17, and Th1 cells after 48 hours in polarization conditions Overall design: We profiled in vitro polarized and in vivo mouse primary CD4 T cells inon-pathogenic Th17, pathogenic Th17, and Th1 cells harvested after 48h polarization from naive mouse CD4 T cells using single-cell RNA-seq and single-cell ATAC-seq