Concise Total Synthesis of (−)-Deoxocuscohygrine and (−)-Dihydrocuscohygrine
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The concise enantioselective total synthesis of C2-asymmetrical (−)-deoxocuscohygrine and (−)-dihydrocuscohygrine are described. Double-diastereoselective additions of normal Grignard reagent to bis(1,3-oxazolidine) have been deployed to construct chiral diamine fragments as a key step.
创建时间:
2016-02-26



