Prospective Validation Using an Hitherto Uncharacterized HLA Molecule.

Predictive performance values for the Pan-specific and TEPITOPE [27] methods, respectively, on a set of 256 15mer peptides. The AUC value (area under the operator receiver curve) was calculated using an IC50 binding threshold value of 500 nM. Note, that the Pearson's correlation is not informative for the TEPITOPE method since this method gives large negative (−999) scores to disfavored amino acids on certain positions.