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资源简介：
pHPT and inflammatory changes in adipose tissue
应用场景：
创建时间：
2011-06-01
相关数据集
Gene expression specificity in relation to the main cellular fractions of the adipose tissue. Homo sapiens
In human obesity, the stroma vascular fraction (SVF) of white adipose tissue (WAT) is enriched in macrophages. These cells may contribute to low-grade inflammation and to its metabolic complications.
NIAID Data Ecosystem80
PHPT_DataSet.xlsx
Data set contain data of 464 PHPT patients and 148 healthy controls.
Figshare2021-03-17 更新30
Adipose-derived autotaxin regulates inflammation and steatosis associated with diet-induced obesity
Autotaxin (ATX) is a secreted enzyme that generates the bioactive lipid lysophosphatidic acid (LPA). We generated mice with global inducible post-natal inactivation or adipose-specific loss of the Enp
NIAID Data Ecosystem20
BVT.2733, a Selective 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor, Attenuates Obesity and Inflammation in Diet-Induced Obese Mice
BackgroundInhibition of 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) is being pursued as a new therapeutic approach for the treatment of obesity and metabolic syndrome. Therefore, there is an ur
NIAID Data Ecosystem40
Expression of HPGD in regulatory T cells prevents adipose tissue inflammation and metabolic dysfunction (data set 1)
Regulatory T cells (Treg cells) are important for the prevention of autoimmunity and lately, their role in maintaining tissue homeostasis has been demonstrated. They exert their function via different
NIAID Data Ecosystem20
