Invariant natural killer T (iNKT) cells are a special subset of T cells that recognize lipid antigens. They contribute to both innate and adaptive immunity in infection, chronic inflammation and cance
We performed bulk RNA sequencing of tumor biopsies from patients before treatment, on-treatment and in case a poor response was suspected from the resection specimen. At baseline we found in respondin
TIGIT signaling in NK cells was blocked with anti-TIGIT antibody in the co-culture with cancer spheroids for 7 days. NK cells were selected upon co-culture and RNA sequencing was performed to understa