Top GSAT scores (expressed in standard deviations (SD)) between members of the seven families in the Anoctamin Superfamily†.

The inference of homology is based on the Superfamily Principle. See the Methods section for procedural details. The table shows only the highest scores (columns 5–7) that allow the identification of homology transitivity paths A→B→C→D† (columns 1–4) among all seven families. For each row, the cell corresponding to the comparison score in the transitivity path is shaded (lowest score; see columns 5–7). Notice how families in rows 1, 4, 5, 7 and 8 are related by the same protein; that is B = C, which indicates that the same protein has significant alignments with both Family 1 (A; column 1) and Family 2 (D; column 4).