Annex data for case study on ASPA use (V2.1): developmental neurotoxicity (DNT) hazard of desnitro-imidacloprid (DN-IMI)

The supplementary information contained here refers to an article published in ALTEX in 2026 with first Author M. Luijten and last author M. Leist Data files are given for Annexes I-III for the study “Hazard assessment of the agrochemical contaminant desnitro-imidacloprid (DN-IMI) for developmental neurotoxicity (DNT)” The study has been entered into the ASPA-assist V2.1 platform Information was entered in ASPA-assist, with the objective to showcase the workflow, and to exemplify relevant uses of data and approaches. Completeness in a technical, regulatory and scientific sense was not a goal. Conclusive coverage of all aspects has been actively avoided to limit the size of the document and to facilitate an easy overview. Desnitro-imidacloprid (DN-IMI) was used as query compound to showcase the workflow designed for an ab initio next-generation risk assessment (NGRA). The problem formulation specified as data gap to be addressed: developmental neurotoxicity (DNT) for consumers exposed via contaminated food. The exposure calculations were anchored to data on food residue levels available for the parent compound imidacloprid.