HIPK2 and MED19 are new regulators of androgen receptor in prostate cancer cells

ChEBI2013-01-30 更新2026-07-21 收录

前列腺癌分子机制

受体调控

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-43881 数据链接链接失效反馈

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HIPK2 and MED19 are new regulators of androgen receptor in prostate cancer cells

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2013-01-30

TFEB promotes prostate cancer progression via regulating ABCA2-dependent lysosomal biogenesis

前列腺癌分子机制

基因表达调控

The goals of this study is to find effect of overexpression-TFEB in prostate cancer cell (DU145 cell line). Overall design: To further explore the potential molecular mechanisms of how TFEN affects ca

NIAID Data Ecosystem80

Constitutively Active Androgen Receptor Variants Upregulate Expression of Mesenchymal Markers in Prostate Cancer Cells

前列腺癌分子机制

激素受体功能

Androgen receptor (AR) signaling pathway remains the foremost target of novel therapeutics for castration-resistant prostate cancer (CRPC). However, the expression of constitutively active AR variants

NIAID Data Ecosystem60

Circular RNA hsa_circ_0075542 acts as a sponge for microRNA-1197 to suppress malignant characteristics and promote apoptosis in prostate cancer cells

前列腺癌分子机制

环状RNA功能研究

Numerous differentially expressed circular RNAs (circRNAs) have been identified; however, their roles have not been fully elucidated. Since dysregulated circRNAs may have clinical applications, it is

Taylor & Francis Group2024-02-20 更新10

Examining alterations in gene expression of PC3-wt (PSMA -ve) vs PC3-PSMA (PSMA +ve) cells

前列腺癌分子机制

基因表达谱分析

The biological role of PSMA, a biomarker expressed in prostate cancer and by the neovasculature of solid tumors, remains unknown. Although PSMA processes folates in our duodenum, and in the brain clea

NIAID Data Ecosystem70

5′-Substituted Amiloride Derivatives as Allosteric Modulators Binding in the Sodium Ion Pocket of the Adenosine A 2A Receptor

受体调控

分子药理学

The sodium ion site is an allosteric site conserved among many G protein-coupled receptors (GPCRs). Amiloride 1 and 5-(N,N-hexamethylene)amiloride 2 (HMA) supposedly bind in this sodium ion site and

NIAID Data Ecosystem40

HIPK2 and MED19 are new regulators of androgen receptor in prostate cancer cells

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