Co-complex CYP46A1 with 8114 (3f)
收藏Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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https://pdbj.org/mine/summary/7ls3
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Co-complex CYP46A1 with 8114 (3f) Descriptor: (5-methyl-2-pyridin-4-yl-phenyl)-[4-oxidanyl-4-(phenylmethyl)piperidin-1-yl]methanone, Cholesterol 24-hydroxylase, PROTOPORPHYRIN IX CONTAINING FE Authors: Lane, W, Yano, J. Deposit date: 2021-02-17 Release date: 2021-08-25 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.15 Å) Cite: Discovery of Soticlestat, a Potent and Selective Inhibitor for Cholesterol 24-Hydroxylase (CH24H). J.Med.Chem., 64, 2021
创建时间:
2021-02-17



