Nucleotide binding affinity for the N-domain of Wild Type and mutant proteins.
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The affinity is presented here via the dissociation constant Kd for the complex: N-domain- Mg2+-ATP (left column) and N-domain/ATP (right column). The amino acids belonging to the coordination helices are highlighted in light blue, the deletion of the dynamic loop is shown in purple. No binding (Kd>1 mM), *P<0.05, **P<0.01.
创建时间:
2011-10-27




