Evolutionary properties of communities and DAVID groups in AML 2.3.

Gene evolutionary rates (ERs) take real values from 0 (most conserved) to approximately 6.9 (most variable), and ages take integer values from 0 (oldest) to 12 (youngest). The table is organized as follows. "Comm. Index" is the index of the ten largest communities. "Num. genes" is the number of genes in the community. "Comm. ER" indicates whether the community is significantly hotter (i.e. has a higher ER) or colder (i.e. has a lower ER) than the mean of 300 equally-sized sets of genes randomly selected from the network, with a significance threshold of p = 10−3. "Diff. in mean" is the difference between the mean ER of the community and the mean ER of the 300 randomly selected sets. "p-value" is the significance of the difference. "Comm. age", "Diff. in mean", and "p-value" are the same as previously stated, but for age rather than ER. "DAVID group name" is the name of the DAVID group that DAVID identified as enriched in each community. “Group type” states whether the DAVID group is a protein type (P), location of final gene product (L), biological process (B), or cellular component (C). "Num. genes" is the number of genes in the DAVID group. "DAVID Benjamini" is the significance of the enrichment of the DAVID group, as reported by DAVID. The remaining DAVID group columns are computed in the same manner as the community columns.