Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable TTP
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Structure of human DNA polymerase complexed with N7MG in the template base paired with incoming non-hydrolyzable TTP Descriptor: 5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]thymidine, DNA (5'-D(*CP*CP*GP*AP*CP*(FMG)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*GP*CP*TP*GP*AP*TP*GP*CP*GP*A)-3'), ... Authors: Koag, M.C, Lee, S. Deposit date: 2013-12-19 Release date: 2014-07-02 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (2.532 Å) Cite: Transition-state destabilization reveals how human DNA polymerase beta proceeds across the chemically unstable lesion N7-methylguanine. Nucleic Acids Res., 42, 2014
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2013-12-19



