Anthracene-Tethered Ruthenium(II) Arene Complexes as Tools To Visualize the Cellular Localization of Putative Organometallic Anticancer Compounds
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https://figshare.com/articles/dataset/Anthracene_Tethered_Ruthenium_II_Arene_Complexes_as_Tools_To_Visualize_the_Cellular_Localization_of_Putative_Organometallic_Anticancer_Compounds/2539078
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资源简介：
Anthracene derivatives of ruthenium(II) arene compounds
with 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane
(pta) or a sugar phosphite ligand, viz., 3,5,6-bicyclophosphite-1,2-O-isopropylidene-α-d-glucofuranoside, were
prepared in order to evaluate their anticancer properties compared
to the parent compounds and to use them as models for intracellular
visualization by fluorescence microscopy. Similar IC50 values
were obtained in cell proliferation assays, and similar levels of
uptake and accumulation were also established. The X-ray structure
of [{Ru(η6-C6H5CH2NHCO-anthracene)Cl2(pta)] is also reported.
创建时间：
2012-03-19
