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Hepatocyte FBXW7-dependent activity of nutrient-sensing nuclear receptors controls systemic energy homeostasis and NASH progression

NIAID Data Ecosystem2026-05-01 收录

能量代谢调控

非酒精性脂肪性肝炎(NASH)

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE205847 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-11-16

衰老生物学

能量代谢调控

Aging leads to a gradual decline in physical activity and disrupted energy homeostasis. The NAD+-dependent SIRT6 deacylase regulates aging and metabolism through mechanisms that largely remain unknown

NIAID Data Ecosystem90

WBSCR16 Deficiency Drives Adaptive Metabolic Flexibility Via Impaired Mitochondrial 16S rRNA Maturation

RNA加工

能量代谢调控

Mitochondrial rRNAs play important roles in regulating mtDNA-encoded gene expression and energy metabolism subsequently. However, the proteins that regulate mitochondrial 16S rRNA processing remain po

NIAID Data Ecosystem60

Arabidopsis mTERF15 Is Required for Mitochondrial nad2 Intron 3 Splicing and Functional Complex I Activity

RNA剪接

能量代谢调控

Mitochondria play a pivotal role in most eukaryotic cells, as they are responsible for the generation of energy and diverse metabolic intermediates for many cellular events. During endosymbiosis, appr

Figshare2016-01-15 更新40

Evaluation of Methionine Content in a High-Fat and Choline-Deficient Diet on Body Weight Gain and the Development of Non-Alcoholic Steatohepatitis in Mice

非酒精性脂肪性肝炎(NASH)

蛋氨酸剂量效应

Aim Non-alcoholic steatohepatitis (NASH) is a globally recognized liver disease. A methionine- and choline-deficient diet is used to induce NASH in mice; however, this diet also causes severe body wei

NIAID Data Ecosystem70

Single-Cell Analysis of NASH mouse livers

单细胞转录组学

非酒精性脂肪性肝炎(NASH)

We performed single-cell RNA-sequencing of the livers from WT and SIRT7 KO mice. scRNA-sequencing of the livers from WT and SIRT7 KO mice.

NIAID Data Ecosystem60