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Essential functions of glycans in human epithelia dissected by a CRISPR/Cas9-engineered human organotypic skin model

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NIAID Data Ecosystem2026-03-12 收录
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We used RNA_Seq to quantify cellular transcripts in human immortalized N/TERT-1 keratinocytes upon knock out of genes delineating key subtypes of glycosylation pathways in humans. Overall design: 2 different knock out clones of each B4GALT5, C1GALT1, C1GALT1C1, MGAT1, POFUT1, and POGLUT1, as well as 2 technical replicates of wild type.

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2020-10-07
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