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Iron-Mediated Carboarylation/Cyclization of Propargylanilines with Acetals: A Concise Route to Indeno[2,1‑c]quinolines

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Figshare2016-02-16 更新2026-04-29 收录
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FeCl3- and FeBr3-mediated tandem carboarylation/cyclization of propargylanilines with diethyl benzaldehyde acetals furnished the tetracyclic core of indeno­[2,1-c]­quinolines. 5-Tosyl-6,7-dihydro-5H-indeno­[2,1-c]­quinoline and 7H-indeno­[2,1-c]­quinoline derivatives were obtained in good to excellent yields, respectively, by tuning the FeX3 loadings and/or reaction temperatures.

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2016-02-16
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