调节多样性有助于对哺乳动物饮食变化的不同转录反应
收藏干细胞与再生医学数据中心2023-02-10 更新2024-03-06 收录
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Regulatory innovation is central to the evolution of species. Different nutritional sources are one environmental pressure that can select for novel regulatory elements. Dietary composition changes, including exposure to “western” diets with excess fat content, can lead to transcriptional regulatory changes in the liver. In order to investigate how transcriptional regulatory changes in response to a high fat diet diverge across species, we profiled chromatin accessibility, histone modifications and the transcriptome in livers of rhesus macaques and mice fed high fat and normal diets.
创建时间：
2023-02-10
