Data for: The Role of PKC and PKD in CXCL12 directed Prostate Cancer Migration
收藏NIAID Data Ecosystem2026-03-11 收录
官方服务:
资源简介:
raw data incorporated in powerpoint files
应用场景:
创建时间:
2019-09-21
相关数据集
Next generation sequencing showing miRNA profiles of exosomes derived from DHT-treated CAFs and matched ETOH-treated CAFs
Background: Androgen deprivation therapy (ADT) is the backbone of therapy for advanced prostate cancer (PCa). Despite the good initial response, castration resistance and metastatic progression will i
NIAID Data Ecosystem80
Targeting PRC1 Suppresses Double Negative Prostate Cancer Metastasis by Inhibiting Stemness and Reversing Immune Suppression
The mechanisms that enable immune evasion at metastatic sites are poorly understood. We show that the Polycomb Repressor Complex-1 drives the colonization of the bones and visceral organs in Double-Ne
NIAID Data Ecosystem50
The evolutionary steps from primary to metastatic prostate cancer are largely uncharted, and the ability to use DNA present in body fluids as correlates of aggregate metastatic status is under-examined. We reconstructed phylogenies in ten prostate cancer patients with fatal disease using deep targeted sequencing of the prostate, adjacent and distant organs, as well as plasma, serum, and cerebrospinal fluid at various time points. A total of 163 samples are studied.
The evolutionary steps from primary tumor to metastasis in prostate cancer are largely uncharted, and the ability to use serum, plasma, and cerebrospinal fluid as a correlate of aggregate metastatic t
NIAID Data Ecosystem10
Expression profile of PC-3-derived cell lines after transendothelial migration
Metastatic colonization involves cancer cell lodgment or adherence in the microvasculature and subsequent migration of those cells across the endothelium into a secondary organ site. To study this pr
NIAID Data Ecosystem60
Knockdown of Akt1/2 by CRISPR/Cas9 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo. Knockdown of Akt1/2 by CRISPR/Cas9 suppresses the metastasis of human prostate cancer cells CWR22rv1 in vitro and in vivo
Our findings will initially map out the downstream signal pathways of Akt and AR mutual feedback to regulate CaP metastasis through the study of these scientific assumptions, which will provide target
NIAID Data Ecosystem20



