R-loop accumulation in spliceosome mutant leukemias confers sensitivity to PARP1 inhibition by triggering transcription-replication conflicts
收藏NIAID Data Ecosystem2026-05-01 收录
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资源简介：
Primary AML patient somatic mutation analysis to determine variable allele frequency for the study of repurposing FDA approved PARP inhibitors for patients that carry spliceosome mutations by exploiting R-loop dependent vulnerabilities arising from RNA splicing perturbations
创建时间：
2023-11-15
