ViBrism DB

ViBrism DB is a database for anatomical gene expression maps and topological co-expression network graphs created with original techniques of microtomy-based gene expression measurements, Transcriptome Tomography. The DB is equipped with a WebGL-based 2D/3D visualization platform, BAH viewer, and a network viewer. Users can access a total of 172,022 datasets of coding/non-coding transcripts and lncRNAs, present in the mouse brains at four post-natal stages. Expression maps are seen in the whole anatomical context of 3D MR images of the brains. In situ hybridization images and anatomical area maps are browsable in the same space of 3D expression maps. Created images are shareable using URLs, including scene-setting parameters. The DB is expandable by community activity.ViBrism DB 是一款依托基于切片显微术的原创基因表达检测技术——转录组层析成像（Transcriptome Tomography）构建的解剖学基因表达图谱与拓扑共表达网络图数据库。该数据库搭载了基于WebGL的2D/3D可视化平台BAH viewer与网络可视化工具。用户可访问涵盖小鼠大脑四个出生后发育阶段的总计172022套编码/非编码转录本及长链非编码RNA（lncRNAs）数据集。基因表达图谱可在大脑三维MR图像的完整解剖学语境中呈现。原位杂交图像与解剖学区域图谱可在三维表达图谱的同一空间内浏览。所生成的可视化成果可通过携带场景设置参数的URL进行分享。该数据库支持通过社区共建实现功能扩展。

搜集汇总

背景与挑战

背景概述

ViBrism DB 是一个基于转录组断层扫描技术构建的解剖基因表达图谱和拓扑共表达网络图数据库，包含小鼠大脑四个出生后阶段的17.2万个编码/非编码转录本数据集。它提供WebGL支持的2D/3D可视化平台，允许用户在三维表达图谱中浏览原位杂交图像和解剖区域图，并可通过URL分享生成的图像。