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Konrath2023_genotoxic_stress_induced_IKK_NFkB_signaling

NIAID Data Ecosystem2026-05-01 收录

NF-κB信号通路建模

基因毒性应激响应

数据链接：

https://www.omicsdi.org/dataset/biomodels/MODEL2307130001 数据链接链接失效反馈

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资源简介：

Ordinary differential equation-based model describing the genotoxic stress-induced activation of IKK/ NF-kB signaling.

应用场景：

创建时间：

2023-10-25

前列腺癌分子机制

NF-κB信号通路建模

Molecular research in cancer is one of the largest areas of bioinformatic investigation, but it remains a challenge to understand biomolecular mechanisms in cancer-related pathways from high-throughpu

NIAID Data Ecosystem70

Negative feedback systems for modelling NF-κB transcription factor oscillatory activity

NF-κB信号通路建模

细胞振荡动力学

Low-dimensional negative feedback systems (NFSs) were developed within a signal flow model to describe the oscillatory activities of NF-κB caused by interactions with its inhibitor IκBα. The NFSs were

Taylor & Francis Group2025-04-11 更新50

Protein AND Phosphorylation profiles after genotoxic stress

磷酸化蛋白质组学

基因毒性应激响应

In vitro experiment in mouse embryonic stem cells (B4418) exposed to a single dose of cisplatin (5uM) at a single time-point (4hrs) in order to obtain quantitative protein phosphorylation profiles, by

NIAID Data Ecosystem20

Aggregation under genotoxic conditions in HEK293T and U2OS cells

蛋白质聚集分析

基因毒性应激响应

This dataset consists of 2 independent experiments. The first research aim was to identify the proteins that aggregate in HEK293T cells treated with the chemotherapeutic agent camptothecin (CPT), the

NIAID Data Ecosystem70

Radulescu2008_NFkB_hierarchy_M_24_45_62

NF-κB信号通路建模

系统生物学

NFkB model M(24,45,62) This is a model of NFkB pathway functioning from hierarchy of models of decreasing complexity, created to demonstrate application of model reduction methods proposed

NIAID Data Ecosystem40

Konrath2023_genotoxic_stress_induced_IKK_NFkB_signaling

资源简介：

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