The crystal structure of COVID-19 main protease in complex with an inhibitor minocycline

The crystal structure of COVID-19 main protease in complex with an inhibitor minocycline Descriptor: (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, 3C-like proteinase nsp5 Authors: Singh, A, Jangid, K, Dhaka, P, Tomar, S, Kumar, P. Deposit date: 2024-08-04 Release date: 2025-02-12 Last modified: 2025-04-09 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Structural and Mechanistic Insights into the Main Protease (Mpro) Dimer Interface Destabilization Inhibitor: Unveiling New Therapeutic Avenues against SARS-CoV-2. Biochemistry, 64, 2025