Preeclampsia (PE) is a severe placenta-related pregnancy disease that has been associated with maternal systemic inflammation and immune system disorders. However, the distribution and functional chan
Mean percentage +/- SEM IL-2+ CD4 or CD8+ T cells gated off total CD4+ or CD8+ T cells in PB and at the UPI of healthy and preeclamptic (PE) patients, see also Fig 1C & 1E.
Antiphospholipid antibodies (aPL) confer a high risk for adverse pregnancy outcomes, especially in women with SLE. aPLs can induce pro-inflammatory signaling via TLR8 receptors, but mouse models to st
BackgroundSeveral studies report the role of Regulatory T-cells (Tregs) in the pathophysiology of pregnancy adverse outcomes. ObjectiveThe aim of this systematic review and meta-analysis was to determ
Preeclampsia (PE) affects 5-8% of pregnancies and has detrimental effects on maternal-fetal health. PE is characterized by de novo hypertension after 20 weeks of gestation and end-organ damage. System
