Ewing Sarcoma (EwS) is a EWS-FLI1- fusion driven pediatric bone cancer with high metastatic potential. Cellular plasticity, typically regulated via the Rho-pathway, is a prerequisite for metastasis in

NIAID Data Ecosystem40

microRNA alterations associated to clinical response in advanced stage ovarian cancer patients

卵巢癌生物标志物

MicroRNA表达

microRNA alterations associated to clinical response in advanced stage ovarian cancer patients

ChEBI2012-03-09 更新20

EWS::FLI cooperatively binds at GGAA microsatellites via DBD-a4 helix in TTC-466 [H3K27ac_CnT]

尤文肉瘤分子机制

转录组调控

Multi-omics study of DBD-a4 helix of EWS::FLI to understand the underlying mechanism of transcriptional regulation in Ewing sarcoma cell line: TTC-466 In TTC-466 cells, we knock-down endogenous EWSR1:

NIAID Data Ecosystem40

EWS-FLI1 and HOXD13 control tumor cell plasticity in Ewing sarcoma [CUT&RUN]

尤文肉瘤分子机制

表观遗传调控

Posterior homeobox D genes, in particular HOXD13, are over-expressed by Ewing sarcoma, a tumor driven by the oncogenic fusion protein EWS-FLI1. Here, we have found that EWS-FLI1 maintains HOXD13 expre

NIAID Data Ecosystem30

MicroRNA expression profiling of Ewing sarcoma spheres vs. adherent cells

资源简介：

相关数据集