YY1 Controls Em-3â??RR DNA Loop Formation and Immunoglobulin Heavy Chain Class Switch Recombination.

ChEBI2016-08-06 更新2026-07-12 收录

免疫球蛋白类别转换重组

DNA环形成调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-85259 数据链接链接失效反馈

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资源简介：

YY1 Controls Em-3â??RR DNA Loop Formation and Immunoglobulin Heavy Chain Class Switch Recombination.

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2016-08-06

DataSheet_2_Switch Tandem Repeats Influence the Choice of the Alternative End-Joining Pathway in Immunoglobulin Class Switch Recombination.pdf

免疫球蛋白类别转换重组

DNA双链断裂修复途径选择

Immunoglobulin class switch recombination (CSR) plays an important role in humoral imm\une responses by changing the effector functions of antibodies. CSR occurs between highly repetitive switch (S) s

NIAID Data Ecosystem80

Transgenes of the Mouse Immunoglobulin Heavy Chain Locus, Lacking Distal Elements in the 3′ Regulatory Region, Are Impaired for Class Switch Recombination

免疫球蛋白类别转换重组

细胞基因调控

The immunoglobulin heavy (H) chain class switch is mediated by a deletional recombination event between µ and γ, α, or ε constant region genes. This recombination event is upregulated during immune re

NIAID Data Ecosystem50

53BP1 cooperation with the REV7–shieldin complex underpins DNA structure-specific NHEJ

DNA双链断裂修复

免疫球蛋白类别转换重组

53BP1 governs a specialized, context-specific branch of the classical non-homologous end joining DNA double-strand break repair pathway. Mice lacking 53bp1 (also known as Trp53bp1) are immunodeficient

NIAID Data Ecosystem40

Immunoglobulin class-switch recombination downregulates Blimp1-driven IL-10 production in IgM+CD138hi cells

免疫球蛋白类别转换重组

IL-10产生调控

To determine characterize IL-10 producing CD138hi cells, we compared the global gene expression of primary B220+ B cells in spleen, freshly isolated Venus+ CD138hi cells in bone marrow and spleen of I

NIAID Data Ecosystem70

Molecular characterization of hybridoma subclones spontaneously switching at high frequencies in vitro

免疫球蛋白类别转换重组

杂交瘤细胞基因表达

This is a comparative microarray analysis of 36-65 hybridomas switching at normal low frequencies in vitro vs. selected variants spontaneously switching at 100 fold higher frequencies in vitro. This

NIAID Data Ecosystem50

YY1 Controls Em-3â??RR DNA Loop Formation and Immunoglobulin Heavy Chain Class Switch Recombination.

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