Crystal structure of human DHODH in complex with inhibitor 1223
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Crystal structure of human DHODH in complex with inhibitor 1223 Descriptor: 3-[3,5-bis(fluoranyl)-4-[3-(hydroxymethyl)phenyl]phenyl]benzo[f]benzotriazole-4,9-dione, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... Authors: Yu, Y, Chen, Q. Deposit date: 2019-03-08 Release date: 2020-03-18 Last modified: 2024-03-27 Method: X-RAY DIFFRACTION (1.781 Å) Cite: Bifunctional Naphtho[2,3- d ][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production. J.Med.Chem., 63, 2020
创建时间：
2019-03-08
