Crystal Structure of A173V SARS-CoV-2 Main Protease in Complex with GC376

Crystal Structure of A173V SARS-CoV-2 Main Protease in Complex with GC376 Descriptor: 3C-like proteinase nsp5, N~2~-[(benzyloxy)carbonyl]-N-{(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-L-leucinamide Authors: Papini, C, Kenneson, J, Anderson, K.S. Deposit date: 2024-05-03 Release date: 2025-02-12 Last modified: 2025-03-12 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Exploring Possible Drug-Resistant Variants of SARS-CoV-2 Main Protease (M pro ) with Noncovalent Preclinical Candidate, Mpro61. Acs Bio Med Chem Au, 5, 2025