Bone marrow or peripheral blood sequencing data from children with acute lymphoblastic leukemia

NIAID Data Ecosystem2026-03-13 收录

急性淋巴细胞白血病

糖皮质激素耐药基因突变

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA818462 数据链接链接失效反馈

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资源简介：

Gene mutations related to glucocorticoid resistance in pediatric acute lymphoblastic leukemia

创建时间：

2022-03-22

Transcriptional and DNA binding profiling of CEBPE in REH acute lymphoblastic leukaemia cells using shRNA RNA-Seq and ChIP-Seq

急性淋巴细胞白血病

CEBPE转录因子调控

ChIP-Seq - CEBPE - REH. The ETV6/RUNX1 translocated acute lymphoblastic leukaemia cell line REH was used to perform ChIP-Seq using a CEBPE antibody. Cells were fixed in 1% formaldehyde for 10mins, pri

NIAID Data Ecosystem120

ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia. ESRRB regulates glucocorticoid gene expression in mice and patients with acute lymphoblastic leukemia

急性淋巴细胞白血病

糖皮质激素耐药机制

Synthetic glucocorticoids (GCs), such as dexamethasone and prednisone, remain key components of therapy for patients with lymphoid malignancies. For pediatric patients with acute lymphoblastic leukemi

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SUMOylation inhibition potentiates the glucocorticoid receptor to program growth arrest of acute lymphoblastic leukemia cells. SUMOylation inhibition potentiates the glucocorticoid receptor to program growth arrest of acute lymphoblastic leukemia cells

SUMOylation抑制

急性淋巴细胞白血病

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

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PRED resistant B-ALL

白血病耐药性

急性淋巴细胞白血病

primary ALL cells (B-lineage) resistant to prednisolone by the MTT in vitro sensitivity assay Keywords = ALL Keywords: other

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Mechanistic study of Wee1 kinase inhibition with AZD1775 exposes drug targetable vulnerabilities in acute B-lymphoblastic leukemia. Mechanistic study of Wee1 kinase inhibition with AZD1775 exposes drug targetable vulnerabilities in acute B-lymphoblastic leukemia