THE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000222
收藏Protein Data Bank Japan2024-05-01 更新2026-03-21 收录
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https://pdbj.org/mine/summary/4yjo
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THE KINASE DOMAIN OF HUMAN SPLEEN TYROSINE (SYK) IN COMPLEX WITH GTC000222 Descriptor: 5-chloro-N~2~-(1,1-dioxido-2,3-dihydro-1,2-benzothiazol-6-yl)-N~4~-ethyl-N~4~-(1H-indazol-4-yl)pyrimidine-2,4-diamine, GLYCEROL, Tyrosine-protein kinase SYK Authors: Somers, D.O, Neu, M. Deposit date: 2015-03-03 Release date: 2015-09-30 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.6 Å) Cite: Discovery of GSK143, a highly potent, selective and orally efficacious spleen tyrosine kinase inhibitor. Bioorg. Med. Chem. Lett., 21, 2011
创建时间：
2015-03-03
