SMARCA4 loss-of-function induces cisplatin resistance to activate YAP1-dependent epithelial-to-mesenchymal in triple negative breast cancer

We report transcriptome profiling (RNA-seq) for SMARA4 knock-out to elucidate the association with cisplatin-resistance and SMARCA4 loss-of-function using triple negative breast cancer cell lines. Overall design: RNA-seq with SMARCA4 knock-out and WT from MDA-MB-231 and MDA-MB-468 breast cancer cell lines