首页/数据集/Loading values (i.e., correlation coefficients).

Loading values (i.e., correlation coefficients).

NIAID Data Ecosystem2026-03-07 收录

BACE-1抑制剂虚拟筛选

阿尔茨海默病药物靶点

数据链接：

https://figshare.com/articles/dataset/_Loading_values_i_e_correlation_coefficients_/295918 数据链接链接失效反馈

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资源简介：

*Numbers of BACE-1 inhibitors retrieved in the top 1% of the ranked database.

应用场景：

创建时间：

2012-06-11

BACE1抑制剂设计

阿尔茨海默病药物靶点

BACE1 in complex with 4-(3-(furan-2-carboxamido)phenyl)-1-methyl-5-oxo-4-phenylimidazolidin-2-iminium Descriptor: Beta-secretase 1, L(+)-TARTARIC ACID, N-{3-[(2E,4R)-2-imino-1-methyl-5-oxo-4-phenylimi

Protein Data Bank Japan2024-10-30 更新70

Additional file 1 of Artificial intelligence framework identifies candidate targets for drug repurposing in Alzheimer’s disease

阿尔茨海默病药物靶点

药物重定位

Additional file 1.

Figshare2024-02-16 更新40

Structures of Compounds Showing Inhibitory Activity against BACE-1.

阿尔茨海默病药物靶点

计算机辅助药物设计

Structures of Compounds Showing Inhibitory Activity against BACE-1.

Figshare2015-12-02 更新20

Crystal Structure of mid-region amyloid beta capture by solanezumab

阿尔茨海默病药物靶点

抗体-抗原复合物

Crystal Structure of mid-region amyloid beta capture by solanezumab Descriptor: Amyloid-beta fragment, Fab Heavy Chain, Fab Light Chain Authors: Hermans, S.J, Crespi, G.A.N, Parker, M.W, Miles, L.A. D

Protein Data Bank Japan2024-10-23 更新50

Table 3 in Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease

阿尔茨海默病药物靶点

天然药物筛选

Table 3 Biological activities of isolated Vinca minor alkaloids. CompoundIC50 h AChE ± SEM (μM) aIC50 h BuChE ± SEM (μM) aIC50 POP ± SEM (μM) a% inhibition of GSK-3β SEM b ±logBB cPAMPA (P e; 10 6 cm

NIAID Data Ecosystem30

Loading values (i.e., correlation coefficients).

资源简介：

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