Discovery of Potent, Highly Selective and Efficacious SMARCA2 Degraders - Compound 6
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Discovery of Potent, Highly Selective and Efficacious SMARCA2 Degraders - Compound 6 Descriptor: (12'R)-4'-chloro-9'-(piperidin-4-yl)-5'H-spiro[cyclohexane-1,7'-indolo[1,2-a]quinazolin]-5'-one, ACETATE ION, Isoform Short of Probable global transcription activator SNF2L2, ... Authors: Strickland, C, Rice, C. Deposit date: 2024-10-23 Release date: 2024-12-18 Last modified: 2025-02-05 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Discovery of Potent, Highly Selective, and Efficacious SMARCA2 Degraders. J.Med.Chem., 68, 2025
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2024-10-23
