Comparison of PrP^Sc, infectivity and converting activity by PMCA in the inocula.

* For the brain dilutions, only positive and negative dilutions are indicated. For the edible tissues a semi-quantification is provided. The WB signal was semi-quantified as follows: +++ = a tissue positive in all experiments and with a WB signal between brain dilutions −2 and −3 ++ = a tissue positive in at least 2/3 experiments and with a WB signal similar to brain dilution −3 or less +/− = a tissue positive in 1/3 experiments and with a WB signal below brain dilution −3 ** For the brain dilutions, only positive and negative dilutions are indicated. For the edible tissues a semi-quantification is provided. The bioassay results were categorised as follows (see Table 5 and S2 Fig.) +++ = similar to brain dilution −3 or more efficient ++ = between brain dilutions −3 and −4 + = similar to brain dilution −4 or less efficient Comparison of PrPSc, infectivity and converting activity by PMCA in the inocula.