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Antimycobacterial Activities of the Zanthoxylum leprieurii Metabolite Adubangoamide and non-natural Fagaramide Analogs

NIAID Data Ecosystem2026-05-02 收录

抗分枝杆菌药物发现

天然产物NMR数据

数据链接：

https://zenodo.org/record/14198151 数据链接链接失效反馈

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Record contains primary NMR files (FID) for all compounds

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创建时间：

2025-02-10

蛋白质晶体学

抗分枝杆菌药物发现

The crystal structure of P450 CYP121 in complex with lead compound 7e Descriptor: 4-(imidazol-1-ylmethyl)-3-(4-methoxyphenyl)-1-phenyl-pyrazole, Mycocyclosin synthase, PROTOPORPHYRIN IX CONTAINING FE,

Protein Data Bank Japan2024-05-01 更新50

Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM851

结构生物学

抗分枝杆菌药物发现

Crystal Structure of Dihydrofolate reductase (DHFR) from Mycobacterium ulcerans Agy99 in complex with NADP and inhibitor MAM851 Descriptor: 3-{2-[3-({(6M)-2,4-diamino-6-[2-(trifluoromethyl)phenyl]pyri

Protein Data Bank Japan2024-11-27 更新30

Additional file 1 of Computational guided identification of novel anti-mycobacterial agent proved by in-vitro and in-vivo validation

抗分枝杆菌药物发现

计算药物筛选

Supplementary Material 1.

NIAID Data Ecosystem30

Data_Sheet_1_Extreme Drug Tolerance of Mycobacterium abscessus “Persisters”.PDF

抗分枝杆菌药物发现

持留菌药敏测试

Persistence of infection despite extensive chemotherapy with antibiotics displaying low MICs is a hallmark of lung disease caused by Mycobacterium abscessus (Mab). Thus, the classical MIC assay is a p

NIAID Data Ecosystem40

Spectinomycin Analogs for the Treatment of Mycobacterium abscessus Infections. Spectinomycin Analogs for the Treatment of Mycobacterium abscessus Infections

抗分枝杆菌药物发现

RNA-seq转录组学

Non-tuberculous mycobacteria (NTM) are emerging pathogens with high intrinsic drug resistance. Among rapidly growing NTM species, Mycobacterium abscessus is among the most pathogenic. Standard of care

NIAID Data Ecosystem30

Antimycobacterial Activities of the Zanthoxylum leprieurii Metabolite Adubangoamide and non-natural Fagaramide Analogs

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