Crystal structure of IDH1 R132H mutant in complex with FT-2102
收藏Protein Data Bank Japan2023-10-11 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/6u4j
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of IDH1 R132H mutant in complex with FT-2102 Descriptor: 5-{[(1S)-1-(6-chloro-2-oxo-1,2-dihydroquinolin-3-yl)ethyl]amino}-1-methyl-6-oxo-1,6-dihydropyridine-2-carbonitrile, CHLORIDE ION, CITRATE ANION, ... Authors: Toms, A.V, Lin, J. Deposit date: 2019-08-25 Release date: 2020-03-04 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.11 Å) Cite: Structure-Based Design and Identification of FT-2102 (Olutasidenib), a Potent Mutant-Selective IDH1 Inhibitor. J.Med.Chem., 63, 2020
创建时间：
2019-08-25
