BPA CRISPR screen

NIAID Data Ecosystem2026-05-10 收录

化学遗传学

CRISPRi筛选

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP618453 数据链接链接失效反馈

官方服务：

资源简介：

A genome-wide CRISPR knockout screen performed with the Brunello CRISPR library in HeLa and RPE1 cells to identify genetic determinants of cellular sensitivity to Bisphenol A (BPA).

创建时间：

2025-09-12

filename is formated as : __.h5ad

CRISPRi筛选

单细胞基因组学

h5ad with event frequency stored in adata.X event description saved in adata.var meta data for each Guide-Target pair saved in adata.obs

Figshare2023-06-09 更新70

Genome-scale CRISPRi Perturb-seq on both unstimulated and stimulated Jurkat cells reveals regulators of human T-cell signaling

T细胞信号传导调控

CRISPRi筛选

The goal of the experiment is to identify genes involved in T-cell receptor (TCR) signaling and T-cell activation in human T cells. The Jurkat E6 cell line, engineered to express dCas9-KRAB and transd

NIAID Data Ecosystem20

Genes of CRISPR-Cas9 negative screening.

CRISPRi筛选

肿瘤免疫逃逸

We compared changes in sgRNA abundance between T24 cells challenged and unchallenged by CD8+ T cells, and then performed negative screening (p < 0.01, log2Fold change < −1.0, and good sgRNAs ≥ 5). (X

NIAID Data Ecosystem10

Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis [TargetedCRISPRscreen]

白血病发病机制

CRISPRi筛选

Investigating Bcor target genes in BcorΔE9-10KrasG12D leukaemia with a custom CRISPR dropout screen BcorΔE9-10KrasG12D cell line was transduced with a custom CRISPR library and a dropout screen was pe

NIAID Data Ecosystem30

Essential gene profiles for human pluripotent stem cells identify uncharacterized genes and substrate dependencies. Mair et al.

干细胞鉴定

CRISPRi筛选

Human pluripotent stem cells (hPSCs) provide an invaluable tool for modeling diseases and hold promise for regenerative medicine. For understanding pluripotency and lineage differentiation mechanisms,

NIAID Data Ecosystem20

BPA CRISPR screen

资源简介：

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