Wildtype HIV-1 Reverse Transcriptase in complex with JLJ 578
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Wildtype HIV-1 Reverse Transcriptase in complex with JLJ 578 Descriptor: 8-{2-[2-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethoxy]-4-fluorophenoxy}-6-fluoroindolizine-2-carbonitrile, GLYCEROL, Reverse transcriptase/ribonuclease H, ... Authors: Sasaki, T, Gannam, Z.T.K, Anderson, K.S, Jorgensen, W.L, Lee, W. Deposit date: 2018-06-18 Release date: 2019-07-31 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (3.327 Å) Cite: Molecular and cellular studies evaluating a potent 2-cyanoindolizine catechol diether NNRTI targeting wildtype and Y181C mutant HIV-1 reverse transcriptase. Bioorg.Med.Chem.Lett., 29, 2019
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2018-06-18
