Ca2+ activated K+ channels

Ca2+ activated potassium channels are expressed in neuronal and non-neuronal tissue such as smooth muscle, epithelial cell and sensory cells. Ca2+ activated potassium channels are activated when the Ca2+ ion concentration increased, The efflux of K+ via these channels leads to repolarization/hyperpolarization of the membrane potential which limits the Ca2+ influx though voltage activated Ca2+ channels (VGCC) thereby regulating the influx of Ca2+ flow via VGCC.

钙离子激活的钾离子通道在神经元和非神经元组织中表达，如平滑肌、上皮细胞和感觉细胞。当钙离子浓度增加时，钙离子激活的钾离子通道被激活，通过这些通道的钾离子外流导致膜电位去极化或超极化，从而限制通过电压门控钙离子通道（VGCC）的钙离子流入，进而调节通过VGCC的钙离子流。