Overlap on differentially regulated retinal genes and top canonical pathways as defined by pathways in either Qiagen Ingenuity (IPA) or MetaCore.

Pathways are arranged according to the rank for obese versus lean ZDF rats. The probability for a difference between ZDF obese versus lean and Wistar-STZ versus Wistar respectively, p(FDR), is corrected for multiple testing by a Benjamini-Hochberg false discovery rate (FDR) methodology and shown here is negative common logarithm, -lg p(FDR).